Resources
Publications
1990-'94
High Expression of the DNA methyltransferase gene characterizes human neoplastic cells and progression stages of colon cancer

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WAF1, a Potential Mediator of p53 Tumor Suppression

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1995 - '99
Arrest of the cell cycle by the tumour-suppressor BRCA1 requires the CDK-inhibitor p21WAF1/CiPl

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Regulation of p53 downstream genes

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2000 - '04
Insights into cancer therapeutic design based on p53 and TRAIL receptor signaling

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The role of p53 in chemosensitivity and radiosensitivity

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2005 - '09
Meeting Report: The International Conference on Tumor Progression and Therapeutic Resistance

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Distinct Signaling Pathways in TRAIL- versus Tumor Necrosis Factor-Induced Apoptosis

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2010 - Current
Preliminary observations indicate variable patterns of plasma 5-fluorouracil (5-FU) levels during dose optimization of infusional 5-FU in colorectal cancer patients

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Overcoming Hypoxia-Induced Apoptotic Resistance through Combinatorial Inhibition of GSK-3 b and CDK1

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