Howard Hughes Medical Institute Investigator 1995-2004
Wafik El-Deiry's research is aimed at understanding pathways of cell cycle control and cell death in normal and cancer cells. These efforts may lead to novel diagnostic and/or therapeutic strategies for cancer.
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Quest For Answers
"We're trying to understand how cancer cells die, how they're affected by chemotherapy or newer agents, why they become resistant to certain treatments and how to develop strategies to reverse the resistance," says Wafik El-Deiry, MD, PhD, chief of hematology/oncology at Penn State Hershey Medical Center
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Kuwait Prize In Applied Sciences
Dr. El-Deiry was recognized for his work on tumor suppressor genes including p53 and TRAIL, and mechanisms that determine cancer therapeutic response. Dr. El-Deiry was recognized for developing new strategies targeting cell death for cancer therapy.
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Small Molecule Drug Drives Cancer Cells to Suicide
Cancer researchers have pinned down a molecule that can kick-start the body's own tumour-destroying systems, triggering cell death in cancerous but not healthy tissue in mice.
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